Advancements in pharmacological treatment of NAFLD/MASLD: a focus on metabolic and liver-targeted interventions.
semaglutidetirzepatideliraglutideretatrutide
Gastroenterology reportJan 2024
Safety and efficacy of the new, oral, small-molecule, GLP-1 receptor agonists orforglipron and danuglipron for the treatment of type 2 diabetes and obesity: systematic review and meta-analysis of randomized controlled trials.
orforglipron
Metabolism: clinical and experimentalDec 2023
Phase 1
Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity.
orforglipron
The New England journal of medicineSep 2023
Phase 1
Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: A Phase 1a, blinded, placebo-controlled, randomized, single- and multiple-ascending-dose study in healthy participants.
orforglipron
Diabetes, obesity & metabolismSep 2023
Phase 1
Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: A Phase 1b, multicentre, blinded, placebo-controlled, randomized, multiple-ascending-dose study in people with type 2 diabetes.
orforglipron
Diabetes, obesity & metabolismSep 2023
Phase 2
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA.
retatrutide
Lancet (London, England)Aug 2023
Phase 2
Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.
retatrutide
The New England journal of medicineAug 2023
Phase 2
Efficacy and safety of oral orforglipron in patients with type 2 diabetes: a multicentre, randomised, dose-response, phase 2 study.
semaglutideorforglipron
Lancet (London, England)Aug 2023
Is retatrutide (LY3437943), a GLP-1, GIP, and glucagon receptor agonist a step forward in the treatment of diabetes and obesity?
semaglutidetirzepatideretatrutide
Expert opinion on investigational drugsMay 2023
Retatrutide showing promise in obesity (and type 2 diabetes).
semaglutidetirzepatideretatrutide
Expert opinion on investigational drugsJan 2023
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